Photovoltage generation in enzymatic bio-hybrid architectures

Bio-Inspired Computing Architectures

Functional tooth restoration by next-generation bio-hybrid implant as a bio-hybrid artificial organ replacement therapy

Bio-hybrid artificial organs are an attractive concept to restore organ function through precise biological cooperation with surrounding tissues in vivo. However, in bio-hybrid artificial organs, an artificial organ with fibrous connective tissues, including muscles, tendons and ligaments, has not been developed. Here, we have enveloped with embryonic dental follicle tissue around a HA-coated d...

Designing Usable Bio-information Architectures

Bioinformatics websites offer to the life science large community repositories of information ranging from genes, genomes, proteins, experimental data and their integration, with the aim of supporting the elucidation of biological processes. As the bioinformatics community increasingly relies on the design, sharing and use of web-based resources, it is important to systematically address the us...

Hybrid Analog-Digital Architectures

Signal restoration is necessary to perform computations of significant complexity. In digital computers each state variable is restored to a binary value, but this strategy is incompatible with analog computation. Nevertheless, cortical neurons, whose major mode of operation is analog, are able to perform prodigious feats of computation. Our research on visual cortex suggests that cortical neur...

Tough, bio-inspired hybrid materials.

The notion of mimicking natural structures in the synthesis of new structural materials has generated enormous interest but has yielded few practical advances. Natural composites achieve strength and toughness through complex hierarchical designs that are extremely difficult to replicate synthetically. We emulate nature's toughening mechanisms by combining two ordinary compounds, aluminum oxide...